Manchester United fielded their youngest-ever Premier League starting XI against Brentford on May 4, 2025, as manager Ruben Amorim prioritized the Europa League semi-final.

Manchester United's match against Brentford saw a record-breaking lineup selected by Ruben Amorim. The average age of the starting eleven was just 22 years and 270 days, the youngest in the club's Premier League history. This selection is the third-youngest in Premier League history, only beaten by Middlesbrough (20 years 181 days) and Arsenal (22 years 237 days).

Amorim rested several key players ahead of the crucial Europa League semi-final second leg against Athletic Club. Only Patrick Chinazaekpere Dorgu, Manuel Ugarte and Alejandro Garnacho retained their places, with Chido Obi making his first start.

With United sitting in 14th place in the Premier League, the Europa League offers a potential route to Champions League qualification. The focus on European success suggests a strategic decision to sacrifice league position in the short term for a greater chance of securing a Champions League spot next season. The result of the match vs Brentford is largely inconsequential given the focus on the European semi-final.