FC Barcelona secured a spot in the Champions League Semifinals on April 15, 2025, despite Borussia Dortmund's modified lineup for the second leg of the quarter-finals at Signal Iduna Park. The Catalans entered the match with a significant 4-0 advantage from the first leg.

Barcelona faced Borussia Dortmund in the Champions League quarterfinal second leg with a comfortable lead, leading coach Hans Flick to rest key defender Iñigo Martínez to avoid a potential yellow card suspension for the semifinals. The decision aimed to ensure Martínez's availability for the next stage, where yellow card accumulation would reset.

According to reports, Flick opted for a defensive pairing of Ronald Araújo and Pau Torres to maintain the team's tactical balance. Simultaneously, Dortmund's coach Niko Kovač implemented several changes to his starting XI, influenced by both injuries and strategic considerations. Carney Chukwuemeka was sidelined due to a recurring injury, while Emre Can and Julian Ryerson were rested; Ramy Bensebaini and Yan Couto were given starting opportunities.

Prior to the match, Joan Laporta cautioned against complacency despite the substantial first-leg advantage. The Catalan side aimed to secure a victory, with their 'best trident in Europe' focusing on delivering a strong performance for the Barcelona fans. As the competition advances, Barcelona is set to face the winner of the Bayern Munich vs. Inter Milan clash in the Semifinals.